ACC values included with toxEval.

Downloaded on October 2022 from ToxCast. The data were combined from files in the "INVITRODB_V3_5_LEVEL5" folder. At the time of toxEval package release, this information was found: https://www.epa.gov/comptox-tools/exploring-toxcast-data in the "ToxCast & Tox21 Data Spreadsheet" data set. ACC values are the in the "ACC" column (winning model) and units are log micro-Molarity (log \(\mu\)M).

Source

https://www.epa.gov/comptox-tools/exploring-toxcast-data

Value

data frame with columns CAS, chnm (chemical name), flags, endPoint, and ACC (value).

References

Toxicology, EPA's National Center for Computational (2020): ToxCast and Tox21 Data Spreadsheet. figshare. Dataset. doi:10.23645/epacomptox.6062479.v3 .

Examples

head(ToxCast_ACC)
#>        CAS                                                       flags
#> 1  53-19-0 Only one conc above baseline, active|Less than 50% efficacy
#> 2  53-03-2                                                        <NA>
#> 3  57-91-0                  AC50 less than lowest concentration tested
#> 4  68-22-4                                                        <NA>
#> 5  58-18-4                                                        <NA>
#> 6 797-63-7                                                        <NA>
#>               endPoint       ACC
#> 1 ACEA_AR_agonist_80hr -0.478626
#> 2 ACEA_AR_agonist_80hr -1.358646
#> 3 ACEA_AR_agonist_80hr -3.449847
#> 4 ACEA_AR_agonist_80hr -3.337902
#> 5 ACEA_AR_agonist_80hr -3.689591
#> 6 ACEA_AR_agonist_80hr -3.783135